"Cannabis by Missourians, for Missourians"

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About Us

Show-Me Natural Gardens aims to be one of the first vertically integrated, patient-focused, and family-owned medical cannabis businesses in Southern Missouri. The members behind our company have successfully operated a highly regulated, licensed, and inspected agricultural business—on both a state and federal level—in the State of Missouri for over twenty years. As a family-owned business, Show-Me Natural Gardens strives to personally oversee all aspects of the industry, from seed to sale, maintaining the strictest compliance with regulations and the highest expectations for quality in the business. As industry participants and veteran business entrepreneurs with over ten years in the legal cannabis industry, our team has the skills and dedication to ensure that we are ready to serve the medicinal needs of qualifying Missourians by supplying safe and high-quality cannabis.


Why Cannabis?

Effective, safe, and powerful treatment options for our communities. 


Epilepsy is a neurological condition that affects more than three million Americans. Of those three million, 470,000 cases are children. Children account for 6.3 out of every 1000 cases of epilepsy according to the Center of Disease Control (CDC). The disorder is characterized by seizures, which range from relatively mild (a moment of impaired concentration) to extreme (total loss of consciousness and awareness). Cannabis based medicines – and CBD-dominant products in particular – have proven to be very effective at reducing the frequency and severity of epilepsy seizures.


In 2018, an estimated 1,735,350 new cases of cancer will be diagnosed in the United States and 609,640 people will die from the disease. The number of cancer deaths (cancer mortality) is 163.5 per 100,000 men and women per year (based on 2011–2015 deaths).  Research shows cannabis can drastically reduce the severity of symptoms and improve quality of life for patients. How? Well,  that both THC and CBD (two of the key active components found in cannabis) can stimulate appetite, which may help with the weight loss, anorexia and cachexia that many cancer patients experience. In addition, cannabis is very effective at combating the nausea caused by conventional cancer treatments such as chemotherapy.


HIV/AIDS treatment has come a long way over the last decade or so. While modern therapy allows those with HIV/AIDS to live a long and mostly healthy life, the side effects of the treatment can be challenging to deal with. This is where medicinal cannabis comes in. A number of studies show that medical cannabis can improve many HIV/AIDS-related symptoms, including anorexia, weight loss, severe nausea and more. For instance, a study published in the Journal of Pain Management found 97 percent of HIV patients reported improved appetite with medical cannabis treatment, while 94 percent experienced reduced muscle pain and 93 percent reported improvements to both nausea and anxiety.

Opiod Addiction

On average, 91 Americans are killed every day due to opioid-related drug overdoses. Evidence from research indicates that conventional pharmaceutical intervention on opioid addiction through the use of buprenorphine and methadone pose the risk of harmful drug interaction and related overdose. Research has shown than using cannabis can be an effective way to not only treat pain but to wean addicts off of highly addictive pharmaceuticals.


Anxiety-related disorders affect a huge segment of our population - 40 million adults (18%) in the U.S. age 18 or older .In response, Big Pharma has developed numerous drugs to treat anxiety-related disorders.While these drugs can be effective for many patients, some don’t respond favorably. Researchers have concluded the CBD can significantly reduced anxiety, cognitive impairment, and discomfort in a patient's speech performance.

Palliative Care

According to research published in Current Oncology,  medical cannabis can “provide further relief from distressing symptoms and spiritual suffering”, while improving patients’ overall quality of life. This research is vital in the years ahead as many nations come to terms with aging populations.

Alzheimer's and chronic depression are also receiving their own medical studies showing promising results utilizing Medical Cannabis!

  • Coffee Meet & Greet
    Common Grounds Coffee Shop

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Ava, Missouri 65608

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